| Bioactivity | β2AR agonist 4 (compound A19) is a potent and selective β2-Adrenoceptor agonist with an EC50 of 3.7 pM. β2AR agonist 4 suppresses the inflammatory cytokines and leukocytes upregulation and improves lung function in COPD rat model[1]. |
| Formula | C19H23ClN2O5 |
| Molar Mass | 394.85 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Xing G, et al. Discovery and Identification of Novel 5-Hydroxy-4 H-benzo [1, 4] oxazin-3-one Derivatives as Potent β2-Adrenoceptor Agonists through Structure-Based Design, Synthesis, and Biological Evaluation[J]. Journal of Medicinal Chemistry, 2024. |