Bioactivity | β-Secretase inhibitor ([Asn670, Sta671, Val672]-Amyloid β Peptide (662-675)) is a β-secretase and BACE1 inhibitor (IC50: 25 nM for β-secretase)[1]. |
Name | β-Secretase inhibitor |
CAS | 350228-37-4 |
Sequence | Lys-Thr-Glu-Glu-Ile-Ser-Glu-Val-Asn-{Sta}-Val-Ala-Glu-Phe |
Shortening | KTEEISEVN-{Sta}-VAEF |
Formula | C73H118N16O27 |
Molar Mass | 1651.81 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Lin Liu, et al. A colorimetric strategy for assay of protease activity based on gold nanoparticle growth controlled by ascorbic acid and Cu(II)-coordinated peptide. Sensors and Actuators B: Chemical. Volume 266, 1 August 2018, Pages 246-254. [2]. Zhou Y, et al. Tyrosine-Conjugation Method for Evaluating BACE1 Activity Based on Silver Nanoparticles/Metal-Organic Framework Composites as Electrochemical Tags. Chemistry. 2023 May 16;29(28):e202300450. |