PeptideDB

β-Secretase inhibitor

CAS: 350228-37-4 F: C73H118N16O27 W: 1651.81

β-Secretase inhibitor (-Amyloid β Peptide (662-675)) is a β-secretase and BACE1 inhibitor (IC50: 25 nM for β-secreta
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This product is for research use only, not for human use. We do not sell to patients.

Bioactivity β-Secretase inhibitor ([Asn670, Sta671, Val672]-Amyloid β Peptide (662-675)) is a β-secretase and BACE1 inhibitor (IC50: 25 nM for β-secretase)[1].
Name β-Secretase inhibitor
CAS 350228-37-4
Sequence Lys-Thr-Glu-Glu-Ile-Ser-Glu-Val-Asn-{Sta}-Val-Ala-Glu-Phe
Shortening KTEEISEVN-{Sta}-VAEF
Formula C73H118N16O27
Molar Mass 1651.81
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. Lin Liu, et al. A colorimetric strategy for assay of protease activity based on gold nanoparticle growth controlled by ascorbic acid and Cu(II)-coordinated peptide. Sensors and Actuators B: Chemical. Volume 266, 1 August 2018, Pages 246-254. [2]. Zhou Y, et al. Tyrosine-Conjugation Method for Evaluating BACE1 Activity Based on Silver Nanoparticles/Metal-Organic Framework Composites as Electrochemical Tags. Chemistry. 2023 May 16;29(28):e202300450.