β-Secretase Inhibitor II_product_DataBase

Bioactivity	β-Secretase Inhibitor II is a β-Secretase inhibitor. β-Secretase Inhibitor II is a simple tripeptide aldehyde (IC50=700 nM for inhibition of total Aβ and IC50=2.5 μM for Aβ1–42). β-Secretase Inhibitor II can be used for the research of Alzheimer's disease[1].
Target	IC50: 700 nM (Aβ).IC50: 2.5 μM (Aβ1–42)
Invitro	β-Secretase Inhibitor II is a simple tripeptide aldehyde (IC50=700 nM for inhibition of total Aβ and IC50=2.5 μM for Aβ1–42). β-Secretase Inhibitor II inhibits the formation of both total Aβ and Aβ1–42 in a dose-dependent manner[1].
Name	β-Secretase Inhibitor II
CAS	263563-09-3
Formula	C25H39N3O5
Molar Mass	461.59
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. Abbenante, G., et al. Inhibitors of β-Amyloid Formation Based on the β-Secretase Cleavage Site. Biochemical and Biophysical Research Communications. 2000; 268(1), 133–135.

PeptideDB