PeptideDB

β-S-ARCA triammonium

CAS: F: C22H40N13O17P3S W: 883.62

β-S-ARCA (triammonium) is a mRNA 7-methylguanosine (m7G) cap analog carrying a phosphorothioate (PS) moiety. mRNA incor
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This product is for research use only, not for human use. We do not sell to patients.

Bioactivity β-S-ARCA (triammonium) is a mRNA 7-methylguanosine (m7G) cap analog carrying a phosphorothioate (PS) moiety. mRNA incorporating β-S-ARCA (triammonium) can prolong cellular half-life and increase protein expression. β-S-ARCA (triammonium) can be used in research of mRNA-based anti-cancer vaccines[1].
Formula C22H40N13O17P3S
Molar Mass 883.62
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. Warminski M, et al. Structural Insights into the Interaction of Clinically Relevant Phosphorothioate mRNA Cap Analogs with Translation Initiation Factor 4E Reveal Stabilization via Electrostatic Thio-Effect. ACS Chem Biol. 2021 Feb 19;16(2):334-343.