| Bioactivity | β-Lactamase-IN-7 (compound 14) is a potent VIM-Type metallo-β-lactamase inhibitor, with Kis of 1.26 μM and 0.54 μM for VIM-1 and VIM-4, respectively. β-Lactamase-IN-7 can effectively inhibit Klebsiella pneumoniae[1]. |
| Target | Ki: 1.26 μM (VIM-1), 0.54 μM (VIM-4) |
| Name | β-Lactamase-IN-7 |
| CAS | 2419903-21-0 |
| Formula | C16H15N3S2 |
| Molar Mass | 313.44 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Legru A, et al. 1,2,4-Triazole-3-thione compounds with a 4-ethyl alkyl/aryl sulfide substituent are broad-spectrum metallo-β-lactamase inhibitors with re-sensitization activity. Eur J Med Chem. 2021;226:113873. |
β-Lactamase-IN-7
CAS: 2419903-21-0 F: C16H15N3S2 W: 313.44
β-Lactamase-IN-7 (compound 14) is a potent VIM-Type metallo-β-lactamase inhibitor, with Kis of 1.26 μM and 0.54 μM f
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