| Bioactivity | β-CGRP (mouse) is a calcitonin gene-related peptide that induces vasodilation. β-CGRP (mouse) can be utilized in cardiovascular, pro-inflammatory, migraine and metabolic research[1]. |
| Sequence | Ser-Cys-Asn-Thr-Ala-Thr-Cys-Val-Thr-His-Arg-Leu-Ala-Asp-Leu-Leu-Ser-Arg-Ser-Gly-Gly-Val-Leu-Lys-Asp-Asn-Phe-Val-Pro-Thr-Asp-Val-Gly-Ser-Glu-Ala-Phe-NH2 (Disulfide bridge:Cys2-Cys7) |
| Shortening | SCNTATCVTHRLADLLSRSGGVLKDNFVPTDVGSEAF-NH2 (Disulfide bridge:Cys2-Cys7) |
| Formula | C165H265N49O55S2 |
| Molar Mass | 3879.29 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Whitby K, et al. Castanospermine, a potent inhibitor of dengue virus infection in vitro and in vivo. J Virol. 2005 Jul;79(14):8698-706. [2]. Xu H, et al. Transcriptional Atlas of Intestinal Immune Cells Reveals that Neuropeptide α-CGRP Modulates Group 2 Innate Lymphoid Cell Responses. Immunity. 2019 Oct 15;51(4):696-708.e9. [3]. Arulmani U, et al. Effects of the calcitonin gene-related peptide (CGRP) receptor antagonist BIBN4096BS on alpha-CGRP-induced regional haemodynamic changes in anaesthetised rats. Basic Clin Pharmacol Toxicol. 2004 Jun;94(6):291-7. [4]. Park SH, et al. Role of α-CGRP in the regulation of neurotoxic responses induced by kainic acid in mice. Peptides. 2013 Jun;44:158-62. [5]. McLatchie LM, et al. RAMPs regulate the transport and ligand specificity of the calcitonin-receptor-like receptor. Nature. 1998 May 28;393(6683):333-9. |