| Bioactivity | β-Benzamide adenine dinucleotide is a bioactive metabolite of benzamide nucleoside and a potent inhibitor of inosine 5 '-monophosphate dehydrogenase (IMPDH). β-Benzamide adenine dinucleotide is a potent, competitive inhibitor of human NAD kinase (Ki = 90µM)[1][2]. |
| CAS | 156724-91-3 |
| Formula | C22H28N6O14P2 |
| Molar Mass | 662.44 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Lesiak K, et al. Synthesis of nonhydrolyzable analogues of thiazole-4-carboxamide and benzamide adenine dinucleotide containing fluorine atom at the C2' of adenine nucleoside: induction of K562 differentiation and inosine monophosphate dehydrogenase inhibitory activity. J Med Chem. 1997 Aug 1;40(16):2533-8. [2]. Bonnac L, et al. Probing binding requirements of NAD kinase with modified substrate (NAD) analogues. Bioorg Med Chem Lett. 2007 Mar 15;17(6):1512-5. |
β-Benzamide adenine dinucleotide
CAS: 156724-91-3 F: C22H28N6O14P2 W: 662.44
β-Benzamide adenine dinucleotide is a bioactive metabolite of benzamide nucleoside and a potent inhibitor of inosine 5
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