| Bioactivity | β-Apopicropodophyllin is a nature product that could be isolated from Hyptis wticillata.β-Apopicropodophyllin induces apoptosis by inducing microtubule disruption, DNA damage, cell cycle arrest and ER stress. β-Apopicropodophyllin can be used in research of cancer[1]. |
| Invitro | β-Apopicropodophyllin (0-100 nM; 48和72 h) 对 A549、NCI-H1299 和 NCI-460 细胞系具有抗癌活性，IC50 值分别为 16.9、13.1 和 17.1 nM [1]。β-Apopicropodophyllin (0-20 nM; 24和48小时; A549, NCI-H1299 和 NCI-460细胞系) 破坏细胞内微管的聚合[1]。β-Apopicropodophyllin (0-20 nM; 0-24 h; A549, NCI-H1299 和 NCI-460细胞株) 通过激活 ATM 诱导 DNA 损伤，将细胞周期阻滞在 G2/M 期，诱导内质网应激[1]。β- apoopicropodophyllin (15 和 20 nM; 48小时; A549, NCI-H1299 和 NCI-460 细胞系) 诱导体外凋亡细胞死亡[1]。 Cell Viability Assay[1] Cell Line: |
| Name | β-Apopicropodophyllin |
| CAS | 477-52-1 |
| Formula | C22H20O7 |
| Molar Mass | 396.39 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
β-Apopicropodophyllin
CAS: 477-52-1 F: C22H20O7 W: 396.39
β-Apopicropodophyllin is a nature product that could be isolated from Hyptis wticillata.β-Apopicropodophyllin induces
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