αvβ1 integrin-IN-2

CAS: 2234874-68-9 F: C29H38N4O4 W: 506.64

αvβ1 integrin-IN-2 (compound 32) is a potent inhibitor of integrins ανβ1 and α5β1 with IC50s of 0.9 nM，and 33 nM

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Bioactivity	αvβ1 integrin-IN-2 (compound 32) is a potent inhibitor of integrins ανβ1 and α5β1 with IC50s of 0.9 nM，and 33 nM，respectively. αvβ1 integrin-IN-2 also inhibits other integrins with ，，IC50s of 380 nM (ανβ3)，280 nM (ανβ5)，230 nM (ανβ6)，87 nM (ανβ8)，respectively，in SPRA assay[1].
Name	αvβ1 integrin-IN-2
CAS	2234874-68-9
Formula	C29H38N4O4
Molar Mass	506.64
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. Ruminski PG, et al. Preparation of ((tetrahydronaphthyridinylethoxy)pyrazolyl) butanoic acid as integrin antagonists for the treatment and prevention of diseases. World Intellectual Property Organization, WO2018132268 A1. 2018-07-19.

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