| Bioactivity | αA-Conotoxin OIVA (αA-OIVA) is a selective nAChR antagonist with an IC50 of 56 nM against mammalian fetal muscle nAChR. αA-Conotoxin OIVA is a peptide that can be derived from conotoxin. αA-Conotoxin OIVA paralyzes muscles[1][2]. |
| Name | αA-Conotoxin OIVA |
| CAS | 878027-87-3 |
| Sequence | Cys-Cys-Gly-Val-{Hyp}- Asn-Ala-Ala-Cys-His-{Hyp}-Cys-Val-Cys-Lys-Asn-Thr-Cys-NH2 (Disulfide bridge:Cys1-Cys9;Cys2-Cys14;Cys12-Cys18) |
| Shortening | CCGV-{Hyp}-NAACH-{Hyp}-CVCKNTC-NH2 (Disulfide bridge:Cys1-Cys9;Cys2-Cys14;Cys12-Cys18) |
| Formula | C70H110N24O23S6 |
| Molar Mass | 1848.16 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Teichert RW, et al. A uniquely selective inhibitor of the mammalian fetal neuromuscular nicotinic acetylcholine receptor. J Neurosci. 2005 Jan 19;25(3):732-6. [2]. Teichert RW, et al. AlphaA-Conotoxin OIVA defines a new alphaA-conotoxin subfamily of nicotinic acetylcholine receptor inhibitors. Toxicon. 2004 Aug;44(2):207-14. |
αA-Conotoxin OIVA
CAS: 878027-87-3 F: C70H110N24O23S6 W: 1848.16
αA-Conotoxin OIVA (αA-OIVA) is a selective nAChR antagonist with an IC50 of 56 nM against mammalian fetal muscle
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