| Bioactivity | α2β1 Integrin Ligand Peptide interacts with the α2β1 integrin receptor on the cell membrane and mediates extracellular signals into cells. It is a potential antagonist of collagen receptors[1]. |
| Invitro | α2β1 Integrin Ligand Peptide (DGEA) (0.015-2.0 mM) inhibits SA11, RRV, and Wa infection in a dose-dependent manner and had no effect on CRW-8 infectivity[1].α2β1 Integrin Ligand Peptide induces tyrosine kinase-dependent calcium mobilization in osteoblasts and fibroblasts at concentrations of ≥0.5 mM[1].α2β1 Integrin Ligand Peptide loses its ability to inhibit SA11 binding at 1.0 mM[1]. |
| Name | α2β1 Integrin Ligand Peptide |
| CAS | 134580-64-6 |
| Sequence | Asp-Gly-Glu-Ala |
| Shortening | DGEA |
| Formula | C14H22N4O9 |
| Molar Mass | 390.35 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |