| Bioactivity | α2β1 Integrin Ligand Peptide TFA interacts with the α2β1 integrin receptor on the cell membrane and mediates extracellular signals into cells. It is a potential antagonist of collagen receptors[1]. | ||||||
| Invitro | α2β1 Integrin Ligand Peptide (DGEA) TFA (0.015-2.0 mM) inhibits SA11, RRV, and Wa infection in a dose-dependent manner and had no effect on CRW-8 infectivity[1].α2β1 Integrin Ligand PeptideTFA induces tyrosine kinase-dependent calcium mobilization in osteoblasts and fibroblasts at concentrations of ≥0.5 mM[1].α2β1 Integrin Ligand Peptide TFA loses its ability to inhibit SA11 binding at 1.0 mM[1]. | ||||||
| Name | α2β1 Integrin Ligand Peptide TFA | ||||||
| Sequence | Asp-Gly-Glu-Ala | ||||||
| Shortening | DGEA | ||||||
| Formula | C16H23F3N4O11 | ||||||
| Molar Mass | 504.37 | ||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||
| Storage | Sealed storage, away from moisture and light
*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light) |
α2β1 Integrin Ligand Peptide TFA
CAS: F: C16H23F3N4O11 W: 504.37
α2β1 Integrin Ligand Peptide TFA interacts with the α2β1 integrin receptor on the cell membrane and mediates extrace
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