| Bioactivity | α2AR agonist 1 (compound S6a), a new morpholine-containing pyrimidinone, acts as an agonist of α2-adrenoceptor. α2AR agonist 1 induces a concentration-dependent relaxation on aortic ring pre-contracted with Phenylephrine (HY-B0769; pEC50=6.81). α2AR agonist 1 increases NOx and NO levels in HUVECs[1]. |
| Formula | C16H15N4NaO2 |
| Molar Mass | 318.31 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Silvia Maria de Luna Alves, et al. New morpholine-containing pyrimidinones act on α-adrenoceptors. Eur J Pharmacol. 2024 Jul 6:978:176788. |