| Bioactivity | α-Lipoic Acid Derivative 1 (Compound AN-7) is an α-lipoic acid derivative that enhances glucose transport in skeletal muscle by releasing active α-lipoic acid (LA), significantly improving glucose metabolism. In L6 skeletal muscle cells, α-Lipoic Acid Derivative 1 significantly increases glucose transport rates, approximately 12 times more potent than the parent compound α-lipoic acid (HY-N0492). In a mild diabetic mouse model, 10 mg/kg of α-Lipoic Acid Derivative 1 administered for two weeks significantly reduced blood glucose levels by 39%. α-Lipoic Acid Derivative 1 shows significant potential in research related to glucose metabolism in diabetes[1]. |
| CAS | 691410-93-2 |
| Formula | C19H34N2O2S4 |
| Molar Mass | 450.75 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Gruzman A, et al. Synthesis and characterization of new and potent alpha-lipoic acid derivatives. Bioorg Med Chem. 2004 Mar 1;12(5):1183-90. |
α-lipoic acid derivative 1
CAS: 691410-93-2 F: C19H34N2O2S4 W: 450.75
α-Lipoic Acid Derivative 1 (Compound AN-7) is an α-lipoic acid derivative that enhances glucose transport in skeletal
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