Bioactivity | α-Secretase Substrate, Fluorogenic is α-secretase fluorogenic substrate that can be used to test α-secretase activity[1]. |
Name | α-Secretase Substrate, Fluorogenic |
Sequence | {MCA}-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-{Lys(DNP)} |
Shortening | {MCA}-HQKLVFFA-{Lys(DNP)} |
Formula | C73H94N16O19 |
Molar Mass | 1499.62 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Fukumoto H, et, al. A noncompetitive BACE1 inhibitor TAK-070 ameliorates Abeta pathology and behavioral deficits in a mouse model of Alzheimer's disease. J Neurosci. 2010 Aug 18;30(33):11157-66. |