| Bioactivity | α-Glucosidase-IN-41 (compound 5o) is a potent α-glucosidase inhibitor. α-Glucosidase-IN-41 can arise the changed secondary structure of α-Glu to hinder enzyme catalytic activity. α-Glucosidase-IN-41 can be used for diabetes mellitus research[1]. |
| In Vivo | α-Glucosidase-IN-41 (compound 5o) (20 mg/kg) 与对照组相比，可显著降低小鼠餐后血糖24.45%[1]。 |
| Name | α-Glucosidase-IN-41 |
| Formula | C19H18N6O3S |
| Molar Mass | 410.45 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Feng Q, et al. Synthesis, biological evaluation and action mechanism of 7H-[1,2,4] triazolo [3,4-b] [1,3,4] thiadiazine-phenylhydrazone derivatives as α-glucosidase inhibitors. Eur J Med Chem. 2023 Nov 3;262:115920. |