| Bioactivity | α-Conotoxin PIA is a nicotinic acetylcholine receptor (nAChR) antagonist that targets nAChR subtypes containing α6 and α3 subunits. α-Conotoxin PIA has the potential for the research of Parkinson’s disease, and schizophrenia[1]。 |
| Name | α-Conotoxin PIA |
| CAS | 669050-68-4 |
| Sequence | Arg-Asp-Pro-Cys-Cys-Ser-Asn-Pro-Val-Cys-Thr-Val-His-Asn-Pro-Gln-Ile-Cys-NH2 (Disulfide bridge:Cys4-Cys10;Cys5-Cys18) |
| Shortening | RDPCCSNPVCTVHNPQIC-NH2 (Disulfide bridge:Cys4-Cys10;Cys5-Cys18) |
| Formula | C79H125N27O25S4 |
| Molar Mass | 1981.26 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Seung-Wook Chi, et al. Solution Structure of Alpha-Conotoxin PIA, a Novel Antagonist of alpha6 Subunit Containing Nicotinic Acetylcholine Receptors. Biochem Biophys Res Commun. 2005 Dec 30;338(4):1990-7. |
α-Conotoxin PIA
CAS: 669050-68-4 F: C79H125N27O25S4 W: 1981.26
α-Conotoxin PIA is a nicotinic acetylcholine receptor (nAChR) antagonist that targets nAChR subtypes containing α6 and
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This product is for research use only, not for human use. We do not sell to patients.