| Bioactivity | α-Conotoxin PIA TFA is a nicotinic acetylcholine receptor (nAChR) antagonist that targets nAChR subtypes containing α6 and α3 subunits. α-Conotoxin PIA has the potential for the research of Parkinson’s disease, and schizophrenia[1]。 | ||||||
| Name | α-Conotoxin PIA TFA | ||||||
| Sequence | Arg-Asp-Pro-Cys-Cys-Ser-Asn-Pro-Val-Cys-Thr-Val-His-Asn-Pro-Gln-Ile-Cys-NH2 (Disulfide bridge:Cys4-Cys10;Cys5-Cys18) | ||||||
| Shortening | RDPCCSNPVCTVHNPQIC-NH2 (Disulfide bridge:Cys4-Cys10;Cys5-Cys18) | ||||||
| Formula | C85H128F9N27O31S4 | ||||||
| Molar Mass | 2323.33 | ||||||
| Appearance | Solid | ||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||
| Storage | Sealed storage, away from moisture
*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) |
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| Reference | [1]. Seung-Wook Chi , et al. Solution Structure of Alpha-Conotoxin PIA, a Novel Antagonist of alpha6 Subunit Containing Nicotinic Acetylcholine Receptors. Biochem Biophys Res Commun. 2005 Dec 30;338(4):1990-7. |
α-Conotoxin PIA TFA
CAS: F: C85H128F9N27O31S4 W: 2323.33
α-Conotoxin PIA TFA is a nicotinic acetylcholine receptor (nAChR) antagonist that targets nAChR subtypes containing α6
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