| Bioactivity | α-Conotoxin Im-I is a selective α7/α9 nAChR antagonist, blocking α7 nicotinic receptors with the highest apparent affinity, while having an 8-fold lower affinity for homomeric α9 nicotinic receptors. α-Conotoxin Im-I is toxic and induces seizures in rodents. α-Conotoxin Im-I is a tool for studying neuronal nAChR[1][2]. |
| Name | α-Conotoxin Im-I |
| CAS | 156467-85-5 |
| Shortening | Gly-Cys-Cys-Ser-Asp-Pro-Arg-Cys-Ala-Trp-Arg-Cys-NH2 (Disulfide bridge:Cys2-Cys8;Cys3-Cys12) |
| Formula | C52H78N20O15S4 |
| Molar Mass | 1351.56 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
α-Conotoxin Im-I
CAS: 156467-85-5 F: C52H78N20O15S4 W: 1351.56
α-Conotoxin Im-I is a selective α7/α9 nAChR antagonist, blocking α7 nicotinic receptors with the highest apparent af
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