| Bioactivity | α-Conotoxin AuIB, a potent and selective α3β4 nicotinic acetylcholine receptor (nAChR) antagonist, blocks α3β4 nAChRs expressed in Xenopus oocytes with an IC50 of 0.75 μM[1]. |
| Invitro | α-Conotoxin AuIB blocks the α3β4 receptor with >100-fold higher potency than other receptor subunit combinations, including α2β2, α2β4, α3β2, α4β2, α4β4, and α1β1γδ[1]. |
| Name | α-Conotoxin AuIB |
| CAS | 216299-21-7 |
| Sequence | Gly-Cys-Cys-Ser-Tyr-Pro-Pro-Cys-Phe-Ala-Thr-Asn-Pro-Asp-Cys-NH2 (Disulfide bridge:Cys2-Cys8;Cys3-Cys15) |
| Shortening | GCCSYPPCFATNPDC-NH2 (Disulfide bridge:Cys2-Cys8;Cys3-Cys15) |
| Formula | C65H89N17O21S4 |
| Molar Mass | 1572.76 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
α-Conotoxin AuIB
CAS: 216299-21-7 F: C65H89N17O21S4 W: 1572.76
α-Conotoxin AuIB, a potent and selective α3β4 nicotinic acetylcholine receptor (nAChR) antagonist, blocks α3β4 nACh
Sales Email：peptidedb@qq.com
This product is for research use only, not for human use. We do not sell to patients.