| Bioactivity | α-Androstenol (5α-Androst-16-en-3α-ol) is a steroid pheromone that has been found in boar testes and human male axillary sweat. α-Androstenol enhances GABA-activated currents in primary mouse cerebellar granule cells (EC50=0.4 uM). α-Androstenol decreases immobility time in the forced swim test and increases time spent in the open arms of the elevated plus maze in mice. α-Androstenol protects against seizures induced by Pentylenetetrazole or electroshock with anxiolytic-like activity in mice[1][2][3]. |
| CAS | 1153-51-1 |
| Formula | C19H30O |
| Molar Mass | 274.44 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Brooksbank BW, et al. The detection of 5alpha-androst-16-en-3alpha-ol in human male axillary sweat. Experientia. 1974 Aug 15;30(8):864-5. [2]. Kaminski RM, et al. The pheromone androstenol (5 alpha-androst-16-en-3 alpha-ol) is a neurosteroid positive modulator of GABAA receptors. J Pharmacol Exp Ther. 2006 May;317(2):694-703. [3]. Starkenmann C, et al. 5α-Androst-16-en-3α-ol β-D-glucuronide, precursor of 5α-androst-16-en-3α-ol in human sweat. Chem Biodivers. 2013 Dec;10(12):2197-208. |