| Bioactivity | α-Amylase/α-Glucosidase-IN-2 (compound 5) is a potent α-amylase and α-glucosidase dual inhibitor with IC50 values of 13.02, 13.09 µM for α-amylase and α-glucosidase, respectively. α-Amylase/α-Glucosidase-IN-2 has the potential for the research of diabetic complications[1]. |
| Target | IC50: 13.02 µM (α-amylase); 13.09 µM (α-glucosidase). |
| Name | α-Amylase/α-Glucosidase-IN-2 |
| CAS | 2446063-14-3 |
| Formula | C22H16ClN5 |
| Molar Mass | 385.85 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Shamim S, et al. Synthesis and screening of (E)-3-(2-benzylidenehydrazinyl)-5,6-diphenyl-1,2,4-triazine analogs as novel dual inhibitors of α-amylase and α-glucosidase. Bioorg Chem. 2020 Aug;101:103979. |
α-Amylase/α-Glucosidase-IN-2
CAS: 2446063-14-3 F: C22H16ClN5 W: 385.85
α-Amylase/α-Glucosidase-IN-2 (compound 5) is a potent α-amylase and α-glucosidase dual inhibitor with IC50 values of
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