| Bioactivity | α-Amylase/α-Glucosidase-IN-12 (compound 10k) is a dual inhibitor targeting α-glucosidase and α-amylase with IC50 of 34.52 nM and 24.62 nM, respectively. α-Amylase/α-Glucosidase-IN-12 is an inhibitor designed based on triazolo[4,3-b][1,2,4]triazine and has the potential to be used in diabetes research.[11][1]. |
| Target | IC50: 34.52 nM (α-Glucosidase), 24.62 nM (α-Amylase) |
| Invitro | α-Amylase/α-Glucosidase-IN-12 与 α-葡萄糖苷酶的 Ki 值为 33.85 nM[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> α-Amylase/α-Glucosidase-IN-12 相关抗体: |
| Formula | C19H13F3N6OS |
| Molar Mass | 430.41 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Seyfi S, et al. Synthesis, biological activities, and molecular docking studies of triazolo[4,3-b]triazine derivatives as a novel class of α-glucosidase and α-amylase inhibitors. Arch Pharm (Weinheim). 2024 Mar 19:e2300628. |
α-Amylase/α-Glucosidase-IN-12
CAS: F: C19H13F3N6OS W: 430.41
α-Amylase/α-Glucosidase-IN-12 (compound 10k) is a dual inhibitor targeting α-glucosidase and α-amylase with IC50 of
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