| Bioactivity | trans-Zeatin is a plant cytokinin, which plays an important role in cell growth, differentiation, and division; trans-Zeatin also inhibits UV-induced MEK/ERK activation. | |||||||||
| Invitro | trans-Zeatin is a plant cytokinin, which plays an important role in cell growth, differentiation, and division[1]. trans-Zeatin (20, 40 or 80 μM) inhibits UV-induced MEK/ERK activation, upregulates AQP3 in a time- and dose-dependent manner, and attenuates UV induced loss of AQP3 in keratinocytes (HaCaT cells). UV-induced AQP3 downregulation is blocked by MEK/ERK inhibitors. Trans-Zeatin (80 μM) attenuates UV-induced downregulation of wound healing and water permeability in HaCaT cells[2]. | |||||||||
| Name | trans-Zeatin | |||||||||
| CAS | 1637-39-4 | |||||||||
| Formula | C10H13N5O | |||||||||
| Molar Mass | 219.24 | |||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | |||||||||
| Storage |
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