| Bioactivity | trans-Resveratrol-3-O-β-D-Glucuronide is an active metabolite of trans-resveratrol. trans-Resveratrol-3-O-β-D-Glucuronide reduces the proliferation of several intestinal cancer cell line. trans-Resveratrol-3-O-β-D-Glucuronide increases pyruvate production in livers[1][2][3]. |
| Invitro | trans-Resveratrol-3-O-β-D-Glucuronide (48 h) 对 CCL-228、Caco-2 和 HCT-116细胞的增殖具有抑制作用，IC50值 分别为 15.8 μM、16.5 μM 和 10.1 μM[2]。 trans-Resveratrol-3-O-β-D-Glucuronide (30 μM, 48 h) 诱导 CCL-228、Caco-2 和 HCT-116 细胞阻滞在S期[2]。trans-Resveratrol-3-O-β-D-Glucuronide (200 μM, 10分钟) 可增加完全弗氏佐剂诱导的关节炎模型大鼠肝脏中丙酮酸的生成[3]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> trans-Resveratrol-3-O-β-D-Glucuronide 相关抗体: Cell Viability Assay[2] Cell Line: |
| CAS | 387372-17-0 |
| Formula | C20H20O9 |
| Molar Mass | 404.37 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Rousova J, et al. Determination of trans-resveratrol and its metabolites in rat serum using liquid chromatography with high-resolution time of flight mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci. 2016;1039:35-43. [2]. Polycarpou E, et al. Resveratrol 3-O-D-glucuronide and resveratrol 4'-O-D-glucuronide inhibit colon cancer cell growth: evidence for a role of A3 adenosine receptors, cyclin D1 depletion, and G1 cell cycle arrest. Mol Nutr Food Res. 2013;57(10):1708-1717. [3]. Simões MS, et al. Resveratrol biotransformation and actions on the liver metabolism of healthy and arthritic rats. Life Sci. 2022;310:120991. |
trans-Resveratrol-3-O-β-D-Glucuronide
CAS: 387372-17-0 F: C20H20O9 W: 404.37
trans-Resveratrol-3-O-β-D-Glucuronide is an active metabolite of trans-resveratrol. trans-Resveratrol-3-O-β-D-Glucuron
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