| Bioactivity | trans-Ned 19, a NAADP antagonist and TPC blocker, suppresses the calcium signal in human umbilical vein endothelial cells (HUVEC) and the rat aorta relaxation in response to low histamine concentrations[1]. | ||||||||||||
| Target | NAADP, TPC, Calcium Channel | ||||||||||||
| Name | trans-Ned 19 | ||||||||||||
| CAS | 1354235-96-3 | ||||||||||||
| Formula | C30H31FN4O3 | ||||||||||||
| Molar Mass | 514.59 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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| Reference | [1]. Zharkich IL, et al. Suppression of Histamine-Induced Relaxation of Rat Aorta and Calcium Signaling in Endothelial Cells by Two-Pore Channel Blocker trans-NED19 and Hydrogen Peroxide. Izv Akad Nauk Ser Biol. 2016 Jul;(4):430-438. |
trans-Ned 19
CAS: 1354235-96-3 F: C30H31FN4O3 W: 514.59
trans-Ned 19, a NAADP antagonist and TPC blocker, suppresses the calcium signal in human umbilical vein endothelial cell
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