| Bioactivity | trans-4’-Hydroxy CCNU Lomustine-d4 is the deuterium labeled trans-4’-Hydroxy CCNU Lomustine[1]. | ||||||||||||
| Invitro | Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1]. | ||||||||||||
| Name | trans-4’-Hydroxy CCNU Lomustine-d4 | ||||||||||||
| Formula | C9H12D4ClN3O3 | ||||||||||||
| Molar Mass | 253.72 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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| Reference | [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-223. |