Bioactivity | tert-Butyl bromoacetate is a Protac linker that can be used in the synthesis of PROTAC 20S proteasome subunit β5 degrader 2 (HY-169135)[1]. |
CAS | 5292-43-3 |
Formula | C6H11BrO2 |
Molar Mass | 195.05 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Shumei Wang, et al. Discovery of novel 20S proteasome subunit β5 PROTAC degraders as potential therapeutics for pharyngeal carcinoma and Bortezomib-resistant multiple myeloma. Bioorg Chem. 2024 Sep 3:153:107801. |