| Bioactivity | tert-Butyl 2,2,2-trichloroacetimidate is a tert-butylation reagent. tert-Butyl 2,2,2-trichloroacetimidate achieves mild, nonreversible tert-butylation of alcohols and phenols. tert-Butyl 2,2,2-trichloroacetimidate is used in the synthesis of antimicrobial agents[1][2]. | ||||||||||||
| CAS | 98946-18-0 | ||||||||||||
| Formula | C6H10Cl3NO | ||||||||||||
| Molar Mass | 218.51 | ||||||||||||
| Appearance | 21°C 液体 | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
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| Reference | [1]. Fandrick KR, et al. A Noncoordinating Acid-Base Catalyst for the Mild and Nonreversible tert-Butylation of Alcohols and Phenols. J Org Chem. 2021 Mar 19;86(6):4877-4882. [2]. Evans LE, et al. Exploitation of Antibiotic Resistance as a Novel Drug Target: Development of a β-Lactamase-Activated Antibacterial Prodrug. J Med Chem. 2019 May 9;62(9):4411-4425. |
tert-Butyl 2,2,2-trichloroacetimidate
CAS: 98946-18-0 F: C6H10Cl3NO W: 218.51
tert-Butyl 2,2,2-trichloroacetimidate is a tert-butylation reagent. tert-Butyl 2,2,2-trichloroacetimidate achieves mild,
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