| Bioactivity | tDHU, acid is a dihydropyrimidinecereblon ligand that contains an E3 ligase ligand and a benzoic acid linker. tDHU, acid can be used as an E3 ubiquitin ligase ligand-Linker conjugate for the development of PROTACs[1]. |
| Target | cereblon |
| Name | tDHU, acid |
| CAS | 2377643-37-1 |
| Formula | C12H12N2O4 |
| Molar Mass | 248.23 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Novartis AG, et al. Preparation of dihydropyrimidine derivatives as bifunctional degraders for the treatment and prophylaxis of target protein-mediated diseases. World Intellectual Property Organization, WO2021053495 A1 2021-03-25. |
tDHU, acid
CAS: 2377643-37-1 F: C12H12N2O4 W: 248.23
tDHU, acid is a dihydropyrimidinecereblon ligand that contains an E3 ligase ligand and a benzoic acid linker. tDHU, acid
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