| Bioactivity | sulfo-DGN462 sodium is degraded to DGN462 in culture medium and plasma. DGN462, a potent DNA-alkylating agent, shows anti-tumor activity, such as acute myeloid leukemia (AML)[1]. |
| Invitro | DGN462 can be used as a cytotoxic component of antibody-drug conjugates (ADCs). DGN462 is a member of the DNA-alkylating indolinobenzodiazepine pseudodimers (IGNs) class[1]. |
| Name | sulfo-DGN462 sodium |
| CAS | 1401203-09-5 |
| Formula | C53H60N5NaO12S2 |
| Molar Mass | 1046.19 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
sulfo-DGN462 sodium
CAS: 1401203-09-5 F: C53H60N5NaO12S2 W: 1046.19
sulfo-DGN462 sodium is degraded to DGN462 in culture medium and plasma. DGN462, a potent DNA-alkylating agent, shows ant
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