| Bioactivity | smMLCK peptide is a specific inhibitor of smooth muscle myosin light chain kinase (smMLCK). The smMLCK peptide mimics the substrate and competitively inhibits the binding of the actual substrate to the enzyme, thereby inhibiting the kinase activity. This inhibition prevents the phosphorylation of the myosin light chain, thus inhibiting muscle contraction[1]. |
| CAS | 172960-20-2 |
| Sequence | Ala-Arg-Arg-Lys-Trp-Gln-Lys-Thr-Gly-His-Ala-Val-Arg-Ala-Ile-Gly-Arg-Leu-Ser-Ser |
| Shortening | ARRKWQKTGHAVRAIGRLSS |
| Formula | C98H168N38O25 |
| Molar Mass | 2278.62 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Hoffman L, et al.Relative Cosolute Size Influences the Kinetics of Protein-Protein Interactions. Biophys J. 2015 Aug 4;109(3):510-20. |
smMLCK peptide
CAS: 172960-20-2 F: C98H168N38O25 W: 2278.62
smMLCK peptide is a specific inhibitor of smooth muscle myosin light chain kinase (smMLCK). The smMLCK peptide mimics th
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