| Bioactivity | rel-Zotatifin is the racemic isomer of Zotatifin, acts as an eIF4A inhibitor with activity less than Zotatifin. Zotatifin (eFT226) is a potent, selective, and well-tolerated eIF4A inhibitor. Zotatifin promotes eIF4A binding to specific mRNA sequences with recognition motifs in the 5’-UTRs (IC50=2 nM) and interferes with the assembly of the eIF4F initiation complex[1]. | ||||||||||||
| Name | rel-Zotatifin | ||||||||||||
| CAS | 2098191-54-7 | ||||||||||||
| Formula | C28H29N3O5 | ||||||||||||
| Molar Mass | 487.55 | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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rel-Zotatifin
CAS: 2098191-54-7 F: C28H29N3O5 W: 487.55
rel-Zotatifin is the racemic isomer of Zotatifin, acts as an eIF4A inhibitor with activity less than Zotatifin. Zotatif
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