| Bioactivity | rel-Boc-Hyp-OMe is the inactive isomer of Boc-Hyp-OMe (HY-65039), and can be used as an experimental control. Boc-Hyp-OMe is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Boc-Hyp-OMe is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1][2]. | ||||||||||||
| Name | rel-Boc-Hyp-OMe | ||||||||||||
| CAS | 1145663-09-7 | ||||||||||||
| Formula | C11H19NO5 | ||||||||||||
| Molar Mass | 245.27 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
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| Reference | [1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017;16(5):315-337. [2]. Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985. |
rel-Boc-Hyp-OMe
CAS: 1145663-09-7 F: C11H19NO5 W: 245.27
rel-Boc-Hyp-OMe is the inactive isomer of Boc-Hyp-OMe (HY-65039), and can be used as an experimental control. Boc-Hyp-OM
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