Bioactivity | pm26TGF-β1 TFA peptide is a peptide that mimics a portion of the human TGF-β1 molecule. pm26TGF-β1 peptide TFA shows high affinity for the TGF-β1 receptor. pm26TGF-β1 peptide TFA displays potent anti-inflammatory properties and does not exhibit neutrophils’ chemoattraction[1][2]. | ||||||
Invitro | The synthetic pm26TGF-β1 peptide (1 μM, 10 μM and 100 μM; 24-48 hours) tested in peripheral blood mononuclear cells (PBMC) significantly down-modulates TNF-α and up-regulates IL-10 responses in an inflammatory microenvironment, leading to regulatory T cells (Treg) phenotype differentiation[1]. | ||||||
Name | pm26TGF-β1 peptide TFA | ||||||
Sequence | Ala-Cys-Glu-Ser-Pro-Leu-Lys-Arg-Gln-Cys-Gly-Gly-Gly-Ser | ||||||
Shortening | ACESPLKRQCGGGS | ||||||
Formula | C56H94F3N19O22S2 | ||||||
Molar Mass | 1506.58 | ||||||
Transport | Room temperature in continental US; may vary elsewhere. | ||||||
Storage | Sealed storage, away from moisture and light
*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light) |