| Bioactivity | pan-KRAS-IN-6 (compound 12) is a potent pan KRAS inhibitor with IC50 values of 9.79 nM (Kras G12D) and 6.03 nM (Kras G12V)[1]. |
| Invitro | pan-KRAS-IN-6 (20 nM； 72 h) 对 ASPC-1 细胞生长活性有很好的抑制效果(IC50=8.8 μm)[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> pan-KRAS-IN-6 相关抗体: Cell Proliferation Assay[1] Cell Line: |
| CAS | 3033565-36-2 |
| Formula | C29H30ClF3N6O3S |
| Molar Mass | 635.10 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. 홍창희, et al. Novel quinazoline compound as kras inhibitor.WO2024063576.2023-09-21 |
pan-KRAS-IN-6
CAS: 3033565-36-2 F: C29H30ClF3N6O3S W: 635.10
pan-KRAS-IN-6 (compound 12) is a potent pan KRAS inhibitor with IC50 values of 9.79 nM (Kras G12D) and 6.03 nM (Kras G12
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