| Bioactivity | pYEEI is a phosphotyrosine-containing tetrapeptide binds to Src SH2 domain with the Kd of 100 nM and with the IC50 of 6.5 μM. pYEEI plays an important role in cancer research[1]. |
| Sequence | {pTyr}-Glu-Glu-Ile |
| Shortening | {pTyr}-EEI |
| Formula | C25H36N3O14P |
| Molar Mass | 633.54 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. R A Grucza, et al. Role of Electrostatic Interactions in SH2 Domain Recognition: Salt-Dependence of Tyrosyl-Phosphorylated Peptide Binding to the Tandem SH2 Domain of the Syk Kinase and the Single SH2 Domain of the Src Kinase. Biochemistry. 2000 Aug 22;39(33):10072-81. |