| Bioactivity | p38α inhibitor 7 (compound 1) is an effective p38α inhibitor with oral efficacy and generally favorable pharmacokinetic properties[1]. |
| CAS | 668981-02-0 |
| Formula | C18H14F2N4O |
| Molar Mass | 340.33 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Amit S. Kalgutkar, et al. Preclinical Pharmacokinetics and Metabolism of 6-(4-(2,5- Difluorophenyl)oxazol-5-yl)-3-isopropyl-[1,2,4]-triazolo[4,3-a] pyridine, a Novel and Selective p38a Inhibitor: Identification of an Active Metabolite in Preclinical Species and Human Liver Microsomes. Biopharm. Drug Dispos. 27: 371–386 (2006). |