p38-α MAPK-IN-1_product_DataBase

CAS: 443913-15-3 F: C27H35N5O3 W: 477.60

p38-α MAPK-IN-1 is an inhibitor of MAPK14 (p38-α), with IC50 of 2300 nM in EFC displacement assay, and 5500 nM in HTRF

This product is for research use only, not for human use. We do not sell to patients.

Bioactivity

p38-α MAPK-IN-1 is an inhibitor of MAPK14 (p38-α), with IC50 of 2300 nM in EFC displacement assay, and 5500 nM in HTRF assay[1].

Target

IC50: 2300 nM (p38-α, in EFC assay), 5500 nM (p38-α, in HTRF assay)

Invitro

p38-α MAPK-IN-1 (Compound 12) is an inhibitor of MAPK14 (p38-α)>, with IC50 of 2300 nM in EFC displacement assay, and 5500 nM in HTRF assay[1].

Name

p38-α MAPK-IN-1

CAS

443913-15-3

Formula

C27H35N5O3

Molar Mass

477.60

Appearance

Solid

Transport

Room temperature in continental US; may vary elsewhere.

Storage

Reference

[1]. Kluter S, et al. Displacement assay for the detection of stabilizers of inactive kinase conformations. J Med Chem. 2010 Jan 14;53(1):357-67.

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