Bioactivity | p-Xylene bis(pyridinium bromide) (compound 21), a cationic charged quencher, is a week bisquaternary AChE and BChE inhibitor with IC50s of 1540 μM and 529 μM, respectively[1][2]. |
CAS | 14208-10-7 |
Formula | C18H18Br2N2 |
Molar Mass | 422.16 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. M Smolarsky, et al. A simple fluorescent method to determine complement-mediated liposome immune lysis. J Immunol Methods. 1977;15(3):255-65. [2]. Kamil Musilek, et al. Preparation and in vitro screening of symmetrical bispyridinium cholinesterase inhibitors bearing different connecting linkage-initial study for Myasthenia gravis implications. Bioorg Med Chem Lett. 2010 Mar 1;20(5):1763-6. |