| Bioactivity | p-Tolylmaleimide (compound 9) is a naphthalimide derivative that has cytotoxic effects on cancer cells. p-Tolylmaleimide can arrest the cell cycle of human acute myeloid leukemia cells K562 in the sub-G0/G1 phase and induce apoptosis[1]. |
| Invitro | p-Tolylmaleimide 抑制人急性髓系白血病细胞 K562 的 IC50s 分别为 24.99 μM (24 h)，6.61 (48 h)，12.10 (72 h)。p-Tolylmaleimide 抑制人急性髓系白血病细胞 Jurkat 的 IC50s 分别为 27.16 μM (24 h)，15.51 (48 h)，3.94 (72 h)[1]。 0 --> p-Tolylmaleimide 相关抗体: |
| Name | p-Tolylmaleimide |
| CAS | 1631-28-3 |
| Formula | C11H9NO2 |
| Molar Mass | 187.19 |
| Appearance | 固体 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | 4°C, protect from light *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light) |
| Reference | [1]. Machado KE, et al. Apoptotic events induced by maleimides on human acute leukemia cell lines. Chem Res Toxicol. 2013 Dec 16;26(12):1904-16. |
p-Tolylmaleimide
CAS: 1631-28-3 F: C11H9NO2 W: 187.19
p-Tolylmaleimide (compound 9) is a naphthalimide derivative that has cytotoxic effects on cancer cells. p-Tolylmaleimide
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