| Bioactivity | p-F-HHSiD (p-Fluorohexahydrosiladifenidol) hydrochloride is a selective M3 mAChR antagonist. p-F-HHSiD hydrochloride blocks Acetylcholine-mediated vasodilatation in human umbilical vein endothelial cells (HUVECs)[1][2]. |
| CAS | 175615-76-6 |
| Formula | C20H33ClFNOSi |
| Molar Mass | 386.02 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Eglen RM, et al. Interaction of p-F-HHSiD (p-Fluoro-hexahydrosila-difenidol) at muscarinic receptors in guinea-pig trachea. Naunyn Schmiedebergs Arch Pharmacol. 1990 Oct;342(4):394-9. [2]. He Y, et al. In utero hypoxia attenuated acetylcholine-mediated vasodilatation via CHRM3/p-NOS3 in fetal sheep MCA: role of ROS/ERK1/2. Hypertens Res. 2022 Jul;45(7):1168-1182. |
p-F-HHSiD hydrochloride
CAS: 175615-76-6 F: C20H33ClFNOSi W: 386.02
p-F-HHSiD (p-Fluorohexahydrosiladifenidol) hydrochloride is a selective M3 mAChR antagonist. p-F-HHSiD hydrochloride blo
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