| Bioactivity | o-Diaminobenzene-cinnamic acid-C1-pip is a dual inhibitor of c-Met/HDAC. The IC50 value of o-Diaminobenzene-cinnamic acid-C1-pip for c-Met is 28.92 nM. o-Diaminobenzene-cinnamic acid-C1-pip can induce G0/G1 phase cell cycle arrest and apoptosis in MDA-MB-231 breast cancer cells, and it inhibits the proliferation and invasion of breast cancer cell lines[1]. |
| Formula | C20H24N4O |
| Molar Mass | 336.43 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Wang Z, Shi Z, Yang S, et al. Design and Synthesis of c-Met and HDAC Dual Inhibitors for the Treatment of Breast Cancer[J]. ACS Medicinal Chemistry Letters, 2024. |
o-Diaminobenzene-cinnamic acid-C1-pip
CAS: F: C20H24N4O W: 336.43
o-Diaminobenzene-cinnamic acid-C1-pip is a dual inhibitor of c-Met/HDAC. The IC50 value of o-Diaminobenzene-cinnamic aci
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