| Bioactivity | mTOR inhibitor WYE-23 is a mTOR inhibitor, and IC50 is 0.45 nM. It is selective to PI3Kα and IC50 is 661 nM. mTOR inhibitor WYE-23 has antitumor activity[1][2]. |
| CAS | 1062169-46-3 |
| Formula | C26H32N8O4 |
| Molar Mass | 520.58 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Nikola P. Pavletich et al. mTOR CRYSTALS AND MODULATORS. WO2014176281A1.2014-10-30. [2]. Zask A, et al. ATP-competitive inhibitors of the mammalian target of rapamycin: design and synthesis of highly potent and selective pyrazolopyrimidines. J Med Chem. 2009 Aug 27;52(16):5013-6. |
mTOR inhibitor WYE-23
CAS: 1062169-46-3 F: C26H32N8O4 W: 520.58
mTOR inhibitor WYE-23 is a mTOR inhibitor, and IC50 is 0.45 nM. It is selective to PI3Kα and IC50 is 661 nM. mTOR inhib
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