| Bioactivity | mRNA Cap 2'-O-methyltransferase uses S-adenosylmethionine (SAM) as a methyl donor to add a methyl group at the 2'-O position of the first nucleotide at the 5’ end of Cap-0 mRNA, resulting in Cap-1 structure. Cap-1 structure promotes translation efficiency, increasing subsequent protein expression[1]. |
| Invitro | mRNA Cap 2'-O-methyltransferase CMTR1 可调节某些干扰素刺激基因的表达[1]。 |
| Name | mRNA Cap 2'-O-methyltransferase |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Williams GD, et al. The mRNA Cap 2'-O-Methyltransferase CMTR1 Regulates the Expression of Certain Interferon-Stimulated Genes. mSphere. 2020 May 13;5(3):e00202-20. |