| Bioactivity | mP6 (Myr-FEEERA-OH) is a myristoylated peptide. mP6 inhibits the interaction of Gα13 with integrin β3 without disrupting talin-dependent integrin function. mP6 can block the GTP usage of Rac1, Rap1, and Rab7, effectively inhibiting the infection of CHO-A24 cells[1]. |
| Target | Integrin β3 |
| Name | mP6 |
| CAS | 2700321-79-3 |
| Sequence | {Myr}-Phe-Glu-Glu-Glu-Arg-Ala |
| Shortening | {Myr}-FEEERA |
| Formula | C47H75N9O14 |
| Molar Mass | 990.15 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Bondu V, et al. Low-affinity binding in cis to P2Y2R mediates force-dependent integrin activation during hantavirus infection. Mol Biol Cell. 2017 Oct 15;28(21):2887-2903. |