| Bioactivity | m-CPBG (1-(3-Chlorophenyl)biguanide) hydrochloride is a selective 5-HT3 agonist. m-CPBG hydrochloride can be used for the research of neurological disease[1]. |
| In Vivo | m-CPBG hydrochloride (80 and 160 nM) 显著减少急性盐负荷引起的水摄入量[1]。m-CPBG hydrochloride (third ventricle injection; 160 nM) 显著抑制低血容量动物的水摄入[1]。m-CPBG hydrochloride (third ventricle injection; 320 nM) 减少缺水大鼠的水摄入量[1]。m-CPBG hydrochloride (central administration） 抑制中枢胆碱能和血管紧张素能通路药理学激活诱导的水摄入[1]。 Animal Model: |
| Name | m-CPBG hydrochloride |
| CAS | 2113-05-5 |
| Formula | C8H11Cl2N5 |
| Molar Mass | 248.11 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Castro L, et al. Central 5-HT(3) receptors and water intake in rats. Physiol Behav. 2002;77(2-3):349-359. |