m-CPBG hydrochloride

CAS: 2113-05-5 F: C8H11Cl2N5 W: 248.11

m-CPBG (1-(3-Chlorophenyl)biguanide) hydrochloride is a selective 5-HT3 agonist. m-CPBG hydrochloride can be used for th

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Bioactivity	m-CPBG (1-(3-Chlorophenyl)biguanide) hydrochloride is a selective 5-HT3 agonist. m-CPBG hydrochloride can be used for the research of neurological disease[1].
In Vivo	m-CPBG hydrochloride (80 and 160 nM) 显著减少急性盐负荷引起的水摄入量[1]。m-CPBG hydrochloride (third ventricle injection; 160 nM) 显著抑制低血容量动物的水摄入[1]。m-CPBG hydrochloride (third ventricle injection; 320 nM) 减少缺水大鼠的水摄入量[1]。m-CPBG hydrochloride (central administration）抑制中枢胆碱能和血管紧张素能通路药理学激活诱导的水摄入[1]。 Animal Model:
Name	m-CPBG hydrochloride
CAS	2113-05-5
Formula	C8H11Cl2N5
Molar Mass	248.11
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. Castro L, et al. Central 5-HT(3) receptors and water intake in rats. Physiol Behav. 2002;77(2-3):349-359.