| Bioactivity | m-3M3FBS is a potent phospholipase C (PLC) activator. m-3M3FBS stimulates superoxide generation in human neutrophils, upregulates intracellular calcium concentration, and stimulates inositol phosphate generation in various cell lines. m-3M3FBS induces monocytic leukemia cell apoptosis[1][2][3]. | ||||||||||||
| Invitro | m-3M3FBS (5-50 μM) stimulates the formation of inositol phosphates in U937 cells[1].m-3M3FBS (50 μM; 24 hours) inhibits the growth of the leukemic cell lines U937 and THP-1, but not primary monocytes[3].m-3M3FBS (50 μM; 24 hours) induces U937 cell apoptosis[3]. Cell Viability Assay[3] Cell Line: | ||||||||||||
| Name | m-3M3FBS | ||||||||||||
| CAS | 200933-14-8 | ||||||||||||
| Formula | C16H16F3NO2S | ||||||||||||
| Molar Mass | 343.36 | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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m-3M3FBS
CAS: 200933-14-8 F: C16H16F3NO2S W: 343.36
m-3M3FBS is a potent phospholipase C (PLC) activator. m-3M3FBS stimulates superoxide generation in human neutrophils, up
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