Bioactivity |
m-3M3FBS is a potent phospholipase C (PLC) activator. m-3M3FBS stimulates superoxide generation in human neutrophils, upregulates intracellular calcium concentration, and stimulates inositol phosphate generation in various cell lines. m-3M3FBS induces monocytic leukemia cell apoptosis[1][2][3]. |
Invitro |
m-3M3FBS (5-50 μM) stimulates the formation of inositol phosphates in U937 cells[1].m-3M3FBS (50 μM; 24 hours) inhibits the growth of the leukemic cell lines U937 and THP-1, but not primary monocytes[3].m-3M3FBS (50 μM; 24 hours) induces U937 cell apoptosis[3]. Cell Viability Assay[3] Cell Line: |
Name |
m-3M3FBS |
CAS |
200933-14-8 |
Formula |
C16H16F3NO2S |
Molar Mass |
343.36 |
Transport |
Room temperature in continental US; may vary elsewhere. |
Storage |
Powder |
-20°C |
3 years |
|
4°C |
2 years |
In solvent |
-80°C |
6 months |
|
-20°C |
1 month |
|