iBRD4-BD1 diTFA_product_DataBase

Bioactivity	iBRD4-BD1 diTFA is selective BRD4 bromodomain inhibitor. iBRD4-BD1 diTFA has inhibition activity for BRD4 bromodomain with an IC50 value of 12 nM. iBRD4-BD1 diTFA can be used for the research of inflammation and oncology[1].
Invitro	iBRD4-BD1 diTFA 对 BET 系列 BRD4-BD1 具有亲和力和选择性，IC50 值为 12 nM[1]。iBRD4-BD1 diTFA 对 BET 系列 BRD4-BD2、BRD3-BD1、BRD3-BD2、BRD2-BD1 和 BRD2-BD2 具有亲和力和选择性，IC50 值分别为 16 μM，1.0 μM，75 μM，80 nM 和 7.1 μM[1]。iBRD4-BD1 (0-50 μM; 72 h) diTFA 在 MM.1S 细胞中具有细胞毒性，EC50 值为 2.3 μM[1]。 0 --> iBRD4-BD1 diTFA 相关抗体:
Name	iBRD4-BD1 diTFA
CAS	2839318-20-4
Formula	C33H32F9N5O5
Molar Mass	749.62
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. Anand Divakaran, et al. Development of an N-Terminal BRD4 Bromodomain-Targeted Degrader. ACS Med Chem Lett. 2022 Sep 29;13(10):1621-1627.

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