| Bioactivity | hnNOS-IN-3 (compound 39) is a selective nNOS inhibitor, with a Ki of 0.32 μM. The nNOS binding of hnNOS-IN-3 is competitive with L-arginine. The selectivity of hnNOS-IN-3 for nNOS versus iNOS (Ki=37 μM) and eNOS (Ki=9.4 μM) is 115-fold and 29-fold, respectively[1]. |
| Name | hnNOS-IN-3 |
| CAS | 163490-78-6 |
| Formula | C10H12ClF3N2S |
| Molar Mass | 284.73 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Shearer BG, et al. Substituted N-phenylisothioureas: potent inhibitors of human nitric oxide synthase with neuronal isoform selectivity. J Med Chem. 1997 Jun 6;40(12):1901-5. |
hnNOS-IN-3
CAS: 163490-78-6 F: C10H12ClF3N2S W: 284.73
hnNOS-IN-3 (compound 39) is a selective nNOS inhibitor, with a Ki of 0.32 μM. The nNOS binding of hnNOS-IN-3 is competi
Sales Email：peptidedb@qq.com
This product is for research use only, not for human use. We do not sell to patients.